The Lacuna Project

lacuna (n.) a gap in a record where something should be

Independent research. Not affiliated with any government, agency, or company.

Exhibit 145

Schedules of controlled substances: temporary placement of 7-hydroxymitragynine and mitragynine (proposed amendment; notice of intent, Federal Register, 14 October 2026)

Exhibit 145 ยท Agency news release

Schedules of controlled substances: temporary placement of 7-hydroxymitragynine and mitragynine (proposed amendment; notice of intent, Federal Register, 14 October 2026)

HHS recommended scheduling thresholds of more than 1 mg of 7-OH per gram in solids or 1 mg per mL in liquids, with a ratio test. On 14 October 2026 DEA published a proposed amendment, a notice of intent, that withdraws its July 2026 notice of intent and uses those thresholds. On a solids basis 1 mg/g is 0.1 percent, twice the 0.050 percent w/w in the July notice.

Source
U.S. Department of Health and Human Services
Date
October 2026
Grade
Primary record
Document
https://www.federalregister.gov/documents/2026/10/14/2026-20943/schedules-of-controlled-substances-temporary-placement-of-7--hydroxymitragynine-and-mitragynine
Accessed
2026-11-09
Cited by
Findings citing this exhibit
Note
HHS release of 9 October 2026 (hhs.gov) is a second source; the Federal Register gives the HHS letter as 8 October.

Cited by

Finding MED-6.8
Reported In October 2026 DEA proposed, in a new notice of intent, to use HHS-recommended 7-OH scheduling thresholds that, for solid products, are twice the limit in its July notice.