The Lacuna Project

lacuna (n.) a gap in a record where something should be

Independent research. Not affiliated with any government, agency, or company.

Exhibit 211

Adverse Health Outcomes in Women Exposed In Utero to Diethylstilbestrol

Exhibit 211 ยท Cohort study

Adverse Health Outcomes in Women Exposed In Utero to Diethylstilbestrol

In utero exposure of women to DES is associated with a high lifetime risk of a broad spectrum of adverse health outcomes.

Tracks reproductive and cancer outcomes decades after prenatal exposure.

Source
Robert N. Hoover and colleagues; New England Journal of Medicine
Date
6 October 2011
Quoted from
Abstract, Conclusions (N Engl J Med 2011;365:1304-1314)
Grade
Peer-reviewed
Document
https://www.nejm.org/doi/full/10.1056/NEJMoa1013961
Accessed
2026-11-09
Cited by
Findings citing this exhibit

Cited by

Finding MED-11.8
Peer-reviewed The 1971 DES study linked maternal treatment to vaginal cancer in daughters, and later cohorts documented additional adverse outcomes decades after prenatal exposure.