Exhibit 153 · Registry analysis
Trends in childhood cancer: incidence and survival analysis over 45 years of SEER data
The incidence of childhood cancer increased from 14.23 cases per 100,000 children in 1975-1979 to 18.89 in 2010-2019, with an average annual percent change of 0.73.
Using NCI's SEER registry data for 1975–2019, the study found US childhood cancer incidence rising from 14.23 per 100,000 in 1975–1979 to 18.89 in 2010–2019, an average annual increase of 0.73 percent. Age-adjusted childhood cancer mortality fell from 4.9 to 2.3 per 100,000. Five-year survival rose from 63.1 to 85.2 percent.
- Source
- Iyad Sultan, Ahmad S. Alfaar, Yaseen Sultan, Zeena Salman, Ibrahim Qaddoumi; PLoS ONE
- Date
- 3 January 2025
- Quoted from
- Abstract, Results (PLoS ONE 20(1):e0314592)
- Grade
- Peer-reviewed
- Document
- https://doi.org/10.1371/journal.pone.0314592
- Accessed
- 2026-11-09
- Cited by
- Findings citing this exhibit
- Note
- A 2024 Frontiers in Pediatrics analysis of SEER 1975–2018 reports a consistent annual increase of 0.8 percent (https://doi.org/10.3389/fped.2024.1357093).